I could transcribe some quotes, but then you’d miss the thrill in Guillermo del Toro’s voice, however oblique his explanation may be. Among other things (I hope beyond our imagination to guess) The Film Stage guesses correctly that Del Toro is talking about Cuarón’s use of long takes:
It has been said the film has at least a 20-minute single opening scene, with possibly the entire film being made up of just a few shots. If one matches that with the fact that every element must convincingly be in zero gravity, these “mindblowing” technological advancements could be to capture both. Considering he is recreating space inside a studio, and Cuarón’s insistence on photo-real CGI, this continues to be most-anticipated film of 2012.